Lactoferrin to improve iron status

NHMRC LACTOFERRIN EVALUATION IN ANAEMIA OF PREGNANCY STUDY

The LEAP study is evaluating the effects of treatment with oral bovine lactoferrin (bLF) versus iron sulphate (FeSO4) in iron deficiency anaemia in pregnancy (IDAP). Oral FeSO4 is the standard treatment for IDAP but it is poorly tolerated. IV or IM injections are alternatives, but they are costly and risk infection. bLF is a dairy protein classified by the FDA as Generally Recognised as Safe (GRAS). It is well established to mediate iron uptake from the gut with no side effects reported. A study in 60 women with IDAP showed bLF reduced anaemia and inflammation more effectively and was better tolerated than standard FeSO4. The LEAP is investigating bLF administration during pregnancy improves foetal growth and neonatal iron status at birth.

Management of obesity in women who are planning to become or are currently pregnant

Presenters: A/Prof Emmanuel Karantanis & Dr Georgia Rigas

Presentation objectives: 1) Discuss with patients in simple terms the importance of the first 1,000 days; 2) Assist women with obesity to gain an appropriately healthy amount of weight during the pregnancy; 3) Provide women with ideas on how to lose some or most of their pregnancy related weight; 4) Identify which pregnant women with obesity should be deemed “high risk” and referred to the appropriate local services.

Dr Georgia Rigas is a Fellow of the RACGP and also Chair of the RACGP SI Obesity Management Network. She is also the senior Bariatric Medical Practitioner at Australia’s first accredited Bariatric Centre of Excellence at St George Private Hospital, Sydney.

Dr Emmanuel Karantanis is a Conjoint Associate Professor of Obstetrics and Gynaecology at the University of New South Wales. He is a consultant Obstetrician and Urogynaecologist at St George Public and Private Hospitals Sydney. He is Deputy Chairman of the Urogynaecology Training Committee with RANZCOG.

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